![]() Patients with mixed histologic subtype were excluded. Objective To characterize sites of metastasis and their association with survival across the 3 most common histologic variants of mRCC: clear cell (ccRCC), papillary (pRCC), and chromophobe (chrRCC).ĭesign, Setting, and Participants In this multicenter, international cohort study, the International mRCC Database Consortium (IMDC) database was used to identify consecutive patients starting systemic therapy for mRCC between 20. ![]() Data reporting on patterns of metastasis in histologic variants of mRCC are sparse. Importance There exists considerable biological and clinical variability between histologic variants of metastatic renal cell carcinoma (mRCC). Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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